ZFIN is now using GRCz12tu for Genomic Data
Gene
ucp3
- ID
- ZDB-GENE-040426-1317
- Name
- uncoupling protein 3
- Symbol
- ucp3 Nomenclature History
- Previous Names
-
- ucp2l
- zgc:63967
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable oxidative phosphorylation uncoupler activity and proton transmembrane transporter activity. Predicted to be involved in adaptive thermogenesis; mitochondrial transmembrane transport; and response to cold. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including brain; eye; heart; integument; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); hypocholesteremia; and obesity. Orthologous to human UCP3 (uncoupling protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63967 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitochondrial carrier protein | Mitochondrial Metabolite Transporter |
|---|---|---|---|---|
| UniProtKB:A8KC25 | InterPro | 309 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers