ZFIN ID: ZDB-GENE-040426-1317
Gene Name: uncoupling protein 3
Gene Symbol: ucp3
Sequence Ontology ID : SO:0000704

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Previous Names: ucp2l, zgc:63967

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have oxidative phosphorylation uncoupler activity; predicted to be involved in adaptive thermogenesis, mitochondrial transmembrane transport, and response to cold; predicted to localize  ...
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63967]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41711 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ucp3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    obesity {Obesity, severe, and type II diabetes} 601665
    DISEASE ASSOCIATED WITH ucp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane transporter activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002030 (1)
  • InterPro:IPR018108 (1)
  • InterPro:IPR023395 (1)
  • InterPro:IPR040062 (1)
  • PROSITE:PS50920 (1)
  • Pfam:PF00153 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ucp3-001 (1) 1676
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ucp3 No data available
    MARKER RELATIONSHIPS
    ucp3Contained in: [BAC] CH211-176G13 (1) (order this)
    ucp3Encodes: [cDNA] MGC:63967 (1) (order this), MGC:174528 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200353 (1) 1698bp
    Genomic GenBank:BX649477 (1) 148317bp
    Select Tool
    Polypeptide UniProtKB:A8KC25 (1) 309aa
    Sequence Clusters UniGene:85272 (1)
    Sequence Information (all 17)
    OTHER ucp3 GENE PAGES
  • Alliance (1)
  • Gene:794081 (1)
  • VEGA:OTTDARG00000019521 (1)
  • Ensembl(GRCz11):ENSDARG00000091209 (2)
  • ORTHOLOGY for ucp3 (Chr: 10)
    CITATIONS (24)