Gene
slc22a7b.1
- ID
- ZDB-GENE-040426-1311
- Name
- solute carrier family 22 member 7b, tandem duplicate 1
- Symbol
- slc22a7b.1 Nomenclature History
- Previous Names
-
- oat2e (1)
- slc22a7b
- zgc:63958
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Located in plasma membrane. Is expressed in several structures, including eye; heart; liver; pleuroperitoneal region; and skeletal muscle. Orthologous to human SLC22A7 (solute carrier family 22 member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63958 (2 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator, sugar transporter-like | Major facilitator superfamily domain | MFS transporter superfamily |
|---|---|---|---|---|
|
UniProtKB:Q7T3D2
|
546 | |||
|
UniProtKB:A0A8M9PNM2
|
560 | |||
|
UniProtKB:A0A8M9PKL4
|
550 | |||
|
UniProtKB:F1Q880
|
546 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
slc22a7b.1-202
(1)
|
Ensembl | 1,914 nt | ||
| mRNA |
slc22a7b.1-201
(1)
|
Ensembl | 1,739 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-183F23 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:63958 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192489 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_200349 (1) | 1770 nt | ||
| Genomic | GenBank:BX005258 (1) | 193078 nt | ||
| Polypeptide | UniProtKB:A0A8M9PNM2 (1) | 560 aa |
- White, R.J., Mackay, E., Wilson, S.W., Busch-Nentwich, E.M. (2022) Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants. eLIFE. 11:
- Chestnut, B., Sumanas, S. (2019) Zebrafish etv2 knock-in line labels vascular endothelial and blood progenitor cells. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(2):245-261
- Dragojević, J., Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2018) In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e. Toxicology in vitro : an international journal published in association with BIBRA. 46:246-256
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Mihaljevic, I., Popovic, M., Zaja, R., Smital, T. (2016) Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). BMC Genomics. 17:626
- Kettleborough, R.N., Busch-Nentwich, E.M., Harvey, S.A., Dooley, C.M., de Bruijn, E., van Eeden, F., Sealy, I., White, R.J., Herd, C., Nijman, I.J., Fényes, F., Mehroke, S., Scahill, C., Gibbons, R., Wali, N., Carruthers, S., Hall, A., Yen, J., Cuppen, E., and Stemple, D.L. (2013) A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature. 496(7446):494-7
- Gomez, G., Lee, J.H., Veldman, M.B., Lu, J., Xiao, X., and Lin, S. (2012) Identification of Vascular and Hematopoietic Genes Downstream of etsrp by Deep Sequencing in Zebrafish. PLoS One. 7(3):e31658
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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