Gene

diabloa

ID
ZDB-GENE-040426-1303
Name
diablo, IAP-binding mitochondrial protein a
Symbol
diabloa Nomenclature History
Previous Names
  • diablo
  • smac (1)
  • zgc:63938
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; intrinsic apoptotic signaling pathway in response to oxidative stress; and neuron apoptotic process. Predicted to act upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Predicted to be active in mitochondrion. Is expressed in several structures, including cardiovascular system; digestive system; lens; pectoral fin; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With diabloa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 64 Alliance Deafness, autosomal dominant 64 614152
Associated With diabloa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR015142 Smac/DIABLO protein
Homologous_superfamily IPR009062 Smac/DIABLO-like superfamily
Domain Details Per Protein
Protein Length Smac/DIABLO-like superfamily Smac/DIABLO protein
UniProtKB:Q7T3E1 265
UniProtKB:A0A0R4IAS6 90
UniProtKB:A0A0R4IUC3 265
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations