plekhf1

ID

ZDB-GENE-040426-1289

Name

pleckstrin homology domain containing, family F (with FYVE domain) member 1

Symbol

plekhf1 Nomenclature History

Previous Names

zgc:63897

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in endosome organization and endosome to lysosome transport. Predicted to be active in early endosome. Is expressed in EVL and periderm. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63897 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plekhf1 Human Ortholog

No data available

Associated With plekhf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000306	FYVE zinc finger
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR017455	Zinc finger, FYVE-related
Domain	IPR037871	Phafin, PH domain
Family	IPR051765	Pleckstrin homology domain-containing family F
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type