Gene
ddb1
- ID
- ZDB-GENE-040426-1272
- Name
- damage-specific DNA binding protein 1
- Symbol
- ddb1 Nomenclature History
- Previous Names
-
- zgc:63840
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Acts upstream of or within negative regulation of apoptotic process and regulation of cell cycle process. Predicted to be active in nucleus and site of double-strand break. Is expressed in blastomere; endoderm; nervous system; pharyngeal arch; and somite. Orthologous to human DDB1 (damage specific DNA binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Hu et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| White-Kernohan syndrome | 619426 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004871 | Cleavage/polyadenylation specificity factor, A subunit, C-terminal |
| Domain | IPR018846 | Cleavage/polyadenylation specificity factor, A subunit, N-terminal |
| Family | IPR050358 | RSE1/DDB1/CFT1/CPSF1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Domain Details Per Protein
| Protein | Length | Cleavage/polyadenylation specificity factor, A subunit, C-terminal | Cleavage/polyadenylation specificity factor, A subunit, N-terminal | RSE1/DDB1/CFT1/CPSF1 | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6PGT6
|
897 |
Interactions and Pathways
No data available
Plasmids
No data available