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Gene

mvb12a

ID
ZDB-GENE-040426-1240
Name
multivesicular body subunit 12A
Symbol
mvb12a Nomenclature History
Previous Names
  • si:ch1073-286c18.3
  • zgc:63691
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable SH3 domain binding activity. Predicted to be involved in several processes, including endosome to lysosome transport via multivesicular body sorting pathway; receptor catabolic process; and virus maturation. Predicted to act upstream of or within protein transport. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Predicted to be active in cytosol. Orthologous to human MVB12A (multivesicular body subunit 12A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mvb12a Human Ortholog
No data available
Associated With mvb12a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023340 UMA domain
Domain IPR023341 MABP domain
Family IPR018798 Multivesicular body subunit 12
Family IPR040335 Multivesicular body subunit 12A
Domain Details Per Protein
Protein Length MABP domain Multivesicular body subunit 12 Multivesicular body subunit 12A UMA domain
UniProtKB:A0A0R4IFD0 62
UniProtKB:A0A0R4IS49 89
UniProtKB:Q7SXX7 275
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations