Gene

eif2d

ID

ZDB-GENE-040426-1226

Name

eukaryotic translation initiation factor 2D

Symbol

eif2d Nomenclature History

Previous Names

lgtn
zgc:63669

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have translation initiation factor activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to colocalize with cytosolic small ribosomal subunit. Orthologous to human EIF2D (eukaryotic translation initiation factor 2D).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6912359 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif2d Human Ortholog

No data available

Associated With eif2d Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001950	SUI1 domain
Domain	IPR002478	PUA domain
Domain	IPR003121	SWIB/MDM2 domain
Domain	IPR004521	Uncharacterised domain CHP00451
Domain	IPR039759	Eukaryotic translation initiation factor 2D, SUI1 domain
Domain	IPR041366	Pre-PUA domain
Domain	IPR048247	Eukaryotic translation initiation factor 2D, N-terminal domain
Domain	IPR048248	Eukaryotic translation initiation factor 2D-like, PUA RNA-binding domain
Family	IPR039757	Eukaryotic translation initiation factor 2D
Homologous_superfamily	IPR015947	PUA-like superfamily
Homologous_superfamily	IPR036877	SUI1 domain superfamily
Homologous_superfamily	IPR036885	SWIB/MDM2 domain superfamily