Gene
pigb
- ID
- ZDB-GENE-040426-1216
- Name
- phosphatidylinositol glycan anchor biosynthesis, class B
- Symbol
- pigb Nomenclature History
- Previous Names
-
- zgc:63658 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63658 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 80 | Alliance | Developmental and epileptic encephalopathy 80 | 618580 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR005599 | GPI mannosyltransferase |
Domain Details Per Protein
| Protein | Length | GPI mannosyltransferase |
|---|---|---|
|
UniProtKB:Q7SXZ1
|
536 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available