ZFIN is now using GRCz12tu for Genomic Data
Gene
ralgps2
- ID
- ZDB-GENE-040426-1212
- Name
- Ral GEF with PH domain and SH3 binding motif 2
- Symbol
- ralgps2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Orthologous to human RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PH-like domain superfamily | Pleckstrin homology domain | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7SXZ6 | InterPro | 510 | ||||||
| UniProtKB:A0AB32TBT0 | InterPro | 568 | ||||||
| UniProtKB:A0A8M1PH81 | InterPro | 594 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ralgps2-201
(1)
|
Ensembl | 1,761 nt | ||
| mRNA |
ralgps2-202
(1)
|
Ensembl | 7,194 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers