Gene

aqr

ID

ZDB-GENE-040426-1189

Name

aquarius intron-binding spliceosomal factor

Symbol

aqr Nomenclature History

Previous Names

zgc:63611 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human AQR (aquarius intron-binding spliceosomal factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63611 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aqr Human Ortholog

No data available

Associated With aqr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032174	RNA helicase aquarius, N-terminal domain
Domain	IPR041677	DNA2/NAM7 helicase, helicase domain
Domain	IPR041679	DNA2/NAM7 helicase-like, C-terminal
Domain	IPR047187	Upf1-like, C-terminal helicase domain
Domain	IPR048966	RNA helicase aquarius, beta-barrel
Domain	IPR048967	RNA helicase aquarius, insertion domain
Family	IPR026300	CWF11 family
Family	IPR045055	DNA2/NAM7-like helicase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Additional Resources	Length	CWF11 family	DNA2/NAM7 helicase, helicase domain	DNA2/NAM7 helicase-like, C-terminal	DNA2/NAM7-like helicase	P-loop containing nucleoside triphosphate hydrolase	RNA helicase aquarius, beta-barrel	RNA helicase aquarius, insertion domain	RNA helicase aquarius, N-terminal domain	Upf1-like, C-terminal helicase domain
UniProtKB:B1H1M2	InterPro	1525

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	aqr-201 (1) Ensembl	Ensembl		858 nt	Select Tool ZFIN BLAST
mRNA	aqr-202 (1) Ensembl	Ensembl		4,575 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations