ZFIN is now using GRCz12tu for Genomic Data

Gene

ubtfl

ID

ZDB-GENE-040426-1159

Name

upstream binding transcription factor, like

Symbol

ubtfl Nomenclature History

Previous Names

zgc:63557 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in positive regulation of transcription by RNA polymerase I and transcription by RNA polymerase I. Predicted to be active in nucleus. Is expressed in adaxial cell; musculature system; and telencephalon. Human ortholog(s) of this gene implicated in childhood-onset neurodegeneration with brain atrophy. Orthologous to human UBTF (upstream binding transcription factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160265 (1 image)
IMAGE:7162689 (1 image)
MGC:63557 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ubtfl Human Ortholog

No data available

Associated With ubtfl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009071	High mobility group box domain
Domain	IPR029215	High mobility group box domain 5
Family	IPR051762	Upstream Binding Factor 1
Homologous_superfamily	IPR036910	High mobility group box domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M2BAL3	InterPro	714
UniProtKB:A0A8M3APU0	InterPro	718
UniProtKB:B0S7C3	InterPro	719
UniProtKB:A0A8M3B7S2	InterPro	718
UniProtKB:A0A8M2BAY0	InterPro	713
UniProtKB:A0A8M2BAP6	InterPro	690
UniProtKB:A0A8M3AQA2	InterPro	696
UniProtKB:A0A8M2BAL7	InterPro	697
UniProtKB:Q7SY36	InterPro	719
UniProtKB:A0AB32TW39	InterPro	690
UniProtKB:A0AB32TX61	InterPro	692
UniProtKB:A0AB32TX71	InterPro	686
UniProtKB:A0AB32TXF4	InterPro	696
UniProtKB:A0AB32TY28	InterPro	707
UniProtKB:A0AB32TY36	InterPro	691
UniProtKB:A0AB32U005	InterPro	713
UniProtKB:A0AB32U033	InterPro	685
UniProtKB:A0AB32U0E3	InterPro	708
UniProtKB:A0AB32U1E9	InterPro	691
UniProtKB:A0AC58GK59	InterPro	718
UniProtKB:A0AC58GK77	InterPro	714
UniProtKB:A0AC58GK92	InterPro	713
UniProtKB:A0AC58GK94	InterPro	714
UniProtKB:A0AC58GK98	InterPro	718
UniProtKB:A0AC58GKA3	InterPro	713
UniProtKB:A0AC58GKB6	InterPro	713
UniProtKB:A0AC58GKC3	InterPro	712
UniProtKB:A0AC58GKC4	InterPro	713
UniProtKB:A0AC58GKC9	InterPro	712
UniProtKB:A0AC58GKD0	InterPro	713
UniProtKB:A0AC58GKE1	InterPro	708
UniProtKB:A0AC58GKE4	InterPro	707
UniProtKB:A0AC58GKF4	InterPro	695
UniProtKB:A0AC58GKG1	InterPro	712
UniProtKB:A0AC58GKG5	InterPro	696
UniProtKB:A0AC58GKH3	InterPro	697
UniProtKB:A0AC58GKI4	InterPro	695
UniProtKB:A0AC58GKI8	InterPro	696
UniProtKB:A0AC58GKI9	InterPro	691
UniProtKB:A0AC58GKJ1	InterPro	717
UniProtKB:A0AC58GKJ8	InterPro	691
UniProtKB:A0AC58GKJ9	InterPro	691
UniProtKB:A0AC58GKK9	InterPro	691
UniProtKB:A0AC58GKL0	InterPro	691
UniProtKB:A0AC58GKM4	InterPro	686
UniProtKB:A0AC58GKM7	InterPro	690
UniProtKB:A0AC58GKN6	InterPro	685
UniProtKB:A0AC58GKQ7	InterPro	685
UniProtKB:A0AC58GKT5	InterPro	692

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ubtfl-201 (1) Ensembl	Ensembl	2,861 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-202 (1) Ensembl	Ensembl	265 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-204 (1) Ensembl	Ensembl	780 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-206 (1) Ensembl	Ensembl	1,898 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-207 (1) Ensembl	Ensembl	666 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-208 (1) Ensembl	Ensembl	523 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-210 (1) Ensembl	Ensembl	678 nt	Select Tool ZFIN BLAST
mRNA	ubtfl-211 (1) Ensembl	Ensembl	3,184 nt	Select Tool ZFIN BLAST
ncRNA	ubtfl-005 (1) Ensembl	Ensembl	757 nt	Select Tool ZFIN BLAST
ncRNA	ubtfl-006 (1) Ensembl	Ensembl	700 nt	Select Tool ZFIN BLAST
ncRNA	ubtfl-007 (1) Ensembl	Ensembl	423 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations