Gene
asl
- ID
- ZDB-GENE-040426-1152
- Name
- argininosuccinate lyase
- Symbol
- asl Nomenclature History
- Previous Names
-
- zgc:63532 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have argininosuccinate lyase activity. Predicted to be involved in arginine biosynthetic process via ornithine. Predicted to localize to cytoplasm. Is expressed in several structures, including ball; lens; liver; pronephric duct; and solid lens vesicle. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and argininosuccinic aciduria. Orthologous to human ASL (argininosuccinate lyase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63532 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
argininosuccinic aciduria | Alliance | Argininosuccinic aciduria | 207900 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR020557 | Fumarate lyase, conserved site |
Domain | IPR022761 | Fumarate lyase, N-terminal |
Domain | IPR029419 | Argininosuccinate lyase, C-terminal |
Family | IPR000362 | Fumarate lyase family |
Family | IPR009049 | Argininosuccinate lyase |
Homologous_superfamily | IPR008948 | L-Aspartase-like |
Homologous_superfamily | IPR024083 | Fumarase/histidase, N-terminal |
Domain Details Per Protein
Protein | Length | Argininosuccinate lyase | Argininosuccinate lyase, C-terminal | Fumarase/histidase, N-terminal | Fumarate lyase, conserved site | Fumarate lyase family | Fumarate lyase, N-terminal | L-Aspartase-like |
---|---|---|---|---|---|---|---|---|
UniProtKB:F1RA91
|
465 | |||||||
UniProtKB:Q7SY44
|
465 |
Interactions and Pathways
No data available
Plasmids
No data available