Gene

traf3ip1

ID

ZDB-GENE-040426-1146

Name

TNF receptor-associated factor 3 interacting protein 1

Symbol

traf3ip1 Nomenclature History

Previous Names

eli (1)
ift54 (1)
mipt3 (1)
elipsa (1)
zgc:63522

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Involved in regulation of microtubule cytoskeleton organization. Acts upstream of or within several processes, including cerebrospinal fluid circulation; nervous system development; and regulation of microtubule polymerization. Predicted to be located in cilium and cytoskeleton. Predicted to be part of intraciliary transport particle B. Predicted to be active in axoneme and ciliary basal body. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Orthologous to human TRAF3IP1 (TRAF3 interacting protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 37 figures from 16 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With traf3ip1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Senior-Loken syndrome 9	616629

Associated With traf3ip1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040468	TRAF3-interacting protein 1, N-terminal
Domain	IPR041476	TRAF3-interacting protein 1, C-terminal domain
Family	IPR018799	TRAF3-interacting protein 1
Homologous_superfamily	IPR042576	TRAF3-interacting protein 1, N-terminal domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A0R4IR02	InterPro	644
UniProtKB:A0A8M2BJU3	InterPro	628
UniProtKB:A0A8M3AWA2	InterPro	643
UniProtKB:Q6PGZ3	InterPro	629
UniProtKB:A0A2R8PWH6	InterPro	637
UniProtKB:A0A8M3B2X0	InterPro	636
UniProtKB:A0A8M9PRZ6	InterPro	622
UniProtKB:A0AB32TWX3	InterPro	636
UniProtKB:A0AB32TXV2	InterPro	621

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	traf3ip1-201 (1) Ensembl	Ensembl	2,241 nt	Select Tool ZFIN BLAST
mRNA	traf3ip1-202 (1) Ensembl	Ensembl	790 nt	Select Tool ZFIN BLAST
mRNA	traf3ip1-203 (1) Ensembl	Ensembl	1,935 nt	Select Tool ZFIN BLAST
mRNA	traf3ip1-204 (1) Ensembl	Ensembl	1,914 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations