Gene
pde10a
- ID
- ZDB-GENE-040426-1115
- Name
- phosphodiesterase 10A
- Symbol
- pde10a Nomenclature History
- Previous Names
-
- zgc:56689
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cGMP-mediated signaling and signal transduction. Is expressed in chordo neural hinge; epidermis; nervous system; and notochord. Orthologous to human PDE10A (phosphodiesterase 10A).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56689 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lambert et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR023174 | 3'5'-cyclic nucleotide phosphodiesterase, conserved site |
Domain | IPR002073 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
Domain | IPR003018 | GAF domain |
Domain | IPR003607 | HD/PDEase domain |
Family | IPR023088 | 3'5'-cyclic nucleotide phosphodiesterase |
Homologous_superfamily | IPR029016 | GAF-like domain superfamily |
Homologous_superfamily | IPR036971 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily |
Domain Details Per Protein
Protein | Length | 3'5'-cyclic nucleotide phosphodiesterase | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | GAF domain | GAF-like domain superfamily | HD/PDEase domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M6Z293
|
852 | |||||||
UniProtKB:A0A0R4IJT4
|
794 | |||||||
UniProtKB:A0A8M6Z3S4
|
851 | |||||||
UniProtKB:A0A8M6Z9J5
|
851 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
pde10a-201
(1)
|
Ensembl | 2976 nt | |
mRNA |
pde10a-202
(1)
|
Havana | 2576 nt | |
mRNA |
pde10a-203
(1)
|
Ensembl | 2979 nt |
Interactions and Pathways
No data available
Plasmids
No data available