ZFIN is now using GRCz12tu for Genomic Data
Gene
rnaseh2b
- ID
- ZDB-GENE-040426-1090
- Name
- ribonuclease H2, subunit B
- Symbol
- rnaseh2b Nomenclature History
- Previous Names
-
- zgc:56602
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be part of ribonuclease H2 complex. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and ventral mesenchyme. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2B (ribonuclease H2 subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu349 (4 images)
- MGC:56602 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Aicardi-Goutieres syndrome | Alliance | Aicardi-Goutieres syndrome 2 | 610181 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ribonuclease H2 subunit B | Ribonuclease H2 subunit B, wHTH domain |
|---|---|---|---|---|
| UniProtKB:A0A8M2BF43 | InterPro | 163 | ||
| UniProtKB:Q7ZUH0 | InterPro | 216 | ||
| UniProtKB:A0A8M9QJJ8 | InterPro | 306 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rnaseh2b-203
(1)
|
Ensembl | 520 nt | ||
| mRNA |
rnaseh2b-201
(1)
|
Ensembl | 1,042 nt | ||
| ncRNA |
rnaseh2b-003
(1)
|
Ensembl | 531 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers