Gene
rnaseh2b
- ID
- ZDB-GENE-040426-1090
- Name
- ribonuclease H2, subunit B
- Symbol
- rnaseh2b Nomenclature History
- Previous Names
-
- zgc:56602
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have RNA-DNA hybrid ribonuclease activity. Predicted to be involved in RNA catabolic process and ribonucleotide metabolic process. Predicted to localize to nucleoplasm and ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and ventral mesenchyme. Orthologous to human RNASEH2B (ribonuclease H2 subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56602 (6 images)
- eu349 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Aicardi-Goutieres syndrome | Alliance | Aicardi-Goutieres syndrome 2 | 610181 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ribonuclease H2 subunit B | Ribonuclease H2 subunit B, wHTH domain | Rnh202, triple barrel domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BF43
|
163 | |||
|
UniProtKB:Q7ZUH0
|
216 | |||
|
UniProtKB:A0A8M9QJJ8
|
306 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rnaseh2b-203
(1)
|
Ensembl | 520 nt | ||
| mRNA |
rnaseh2b-201
(1)
|
Ensembl | 1,042 nt | ||
| ncRNA |
rnaseh2b-003
(1)
|
Ensembl | 531 nt |
Interactions and Pathways
No data available
Plasmids
No data available