Gene
lmcd1
- ID
- ZDB-GENE-040426-1067
- Name
- LIM and cysteine-rich domains 1
- Symbol
- lmcd1 Nomenclature History
- Previous Names
-
- zgc:56533 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm. Is expressed in cardiac ventricle and myocardium. Orthologous to human LMCD1 (LIM and cysteine rich domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56533 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Dina et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-lmcd1 | N/A | Dina et al., 2015 |
| MO2-lmcd1 | N/A | Dina et al., 2015 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PET domain | PET testin | Prickle/Espinas/Testin | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AMI6 | InterPro | 281 | ||||
| UniProtKB:E7FCK0 | InterPro | 342 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-91K2 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:56533 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_201070 (1) | 1450 nt | ||
| Genomic | GenBank:BX005105 (1) | 171403 nt | ||
| Polypeptide | UniProtKB:E7FCK0 (1) | 342 aa |
- Giffen, K.P., Liu, H., Kramer, K.L., He, D.Z. (2019) Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Frontiers in neuroscience. 13:1117
- Dina, C., Bouatia-Naji, N., Tucker, N., Delling, F.N., Toomer, K., Durst, R., Perrocheau, M., Fernandez-Friera, L., Solis, J., PROMESA investigators, Le Tourneau, T., Chen, M.H., Probst, V., Bosse, Y., Pibarot, P., Zelenika, D., Lathrop, M., Hercberg, S., Roussel, R., Benjamin, E.J., Bonnet, F., Lo, S.H., Dolmatova, E., Simonet, F., Lecointe, S., Kyndt, F., Redon, R., Le Marec, H., Froguel, P., Ellinor, P.T., Vasan, R.S., Bruneval, P., Markwald, R.R., Norris, R.A., Milan, D.J., Slaugenhaupt, S.A., Levine, R.A., Schott, J.J., Hagege, A.A., Mvp-France, Jeunemaitre, X., Leducq Transatlantic MITRAL Network (2015) Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nature Genetics. 47(10):1206-11
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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