Gene
mtmr8
- ID
- ZDB-GENE-040426-1016
- Name
- myotubularin related protein 8
- Symbol
- mtmr8 Nomenclature History
- Previous Names
-
- si:dkey-286f3.1
- zgc:56405
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits MAP kinase kinase activity. Involved in blood vessel development and phosphatidylinositol 3-kinase signaling. Predicted to localize to nuclear envelope. Is expressed in several structures, including anterior axial hypoblast; immature eye; optic primordium; vasculature; and ventral mesoderm. Orthologous to human MTMR8 (myotubularin related protein 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56405 (22 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR010569 | Myotubularin-like, phosphatase domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Length | Myotubularin-like, phosphatase domain | PH-like domain superfamily | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6TEL0
|
632 | |||||
|
UniProtKB:A0A8M9Q8A5
|
391 |
Interactions and Pathways
No data available
Plasmids
No data available