Gene
idh3a
- ID
- ZDB-GENE-040426-1007
- Name
- isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
- Symbol
- idh3a Nomenclature History
- Previous Names
-
- zgc:56380 (1)
- zgc:85631
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; mesoderm; musculature system; optic tectum; and pronephric duct. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56380 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 90 | Alliance | Retinitis pigmentosa 90 | 619007 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Isocitrate dehydrogenase NAD-dependent | Isocitrate/isopropylmalate dehydrogenase, conserved site | Isopropylmalate dehydrogenase-like domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BAG2 | InterPro | 204 | |||
| UniProtKB:Q6NV33 | InterPro | 365 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available