Gene

gja2

ID
ZDB-GENE-040406-2
Name
gap junction protein, alpha 2
Symbol
gja2 Nomenclature History
Previous Names
  • cx39.9 (1)
  • cx46l (1)
  • zgc:110668
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable gap junction channel activity. Acts upstream of or within cell communication by electrical coupling and slow-twitch skeletal muscle fiber contraction. Predicted to be located in gap junction and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of connexin complex. Is expressed in several structures, including eye; kidney; liver; musculature system; and spinal cord.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Hirata et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gja2 Human Ortholog
No data available
Associated With gja2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017990 Connexin, conserved site
Domain IPR013092 Connexin, N-terminal
Domain IPR019570 Gap junction protein, cysteine-rich domain
Family IPR000500 Connexin
Homologous_superfamily IPR034634 Connexin, C-terminal
Homologous_superfamily IPR038359 Connexin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Connexin Connexin, conserved site Connexin, C-terminal Connexin, N-terminal Connexin, N-terminal domain superfamily Gap junction protein, cysteine-rich domain
UniProtKB:Q8AWR4 353
UniProtKB:B0R0X0 353
UniProtKB:Q503E4 397
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations