Gene
uros
- ID
- ZDB-GENE-040323-2
- Name
- uroporphyrinogen III synthase
- Symbol
- uros Nomenclature History
- Previous Names
-
- wu:fd13d11
- zgc:110240
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable uroporphyrinogen-III synthase activity. Predicted to be involved in uroporphyrinogen III biosynthetic process. Predicted to act upstream of or within tetrapyrrole biosynthetic process. Predicted to be active in cytosol. Is expressed in hematopoietic system; kidney; mesoderm; and notochord. Human ortholog(s) of this gene implicated in cutaneous porphyria. Orthologous to human UROS (uroporphyrinogen III synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912557 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cutaneous porphyria | Alliance | Porphyria, congenital erythropoietic | 263700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tetrapyrrole biosynthesis, uroporphyrinogen III synthase | Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily | Uroporphyrinogen-III synthase |
|---|---|---|---|---|
|
UniProtKB:Q568K6
|
262 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available