Gene
rtn4r
- ID
- ZDB-GENE-040310-1
- Name
- reticulon 4 receptor
- Symbol
- rtn4r Nomenclature History
- Previous Names
-
- NgR
- Nogo-66 receptor
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have Roundabout binding activity and heparin binding activity. Involved in axon guidance and peripheral nervous system neuron axonogenesis. Human ortholog(s) of this gene implicated in schizophrenia. Is expressed in nervous system. Orthologous to human RTN4R (reticulon 4 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92613 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Brösamle et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| schizophrenia | Alliance | {Schizophrenia, susceptibility to} | 181500 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
|---|---|---|---|---|---|
|
UniProtKB:Q6X3Y5
|
479 |
Interactions and Pathways
No data available
Plasmids
No data available