ZFIN is now using GRCz12tu for Genomic Data
Gene

myf6

ID
ZDB-GENE-040309-2
Name
myogenic factor 6
Symbol
myf6 Nomenclature History
Previous Names
  • herculin (1)
  • mrf4 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within skeletal muscle tissue development. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including Rohon-Beard neurons; adaxial cell; fin; muscle precursor cell; and musculature system. Human ortholog(s) of this gene implicated in congenital structural myopathy. Orthologous to human MYF6 (myogenic factor 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Wang et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myf6 Human Ortholog
No data available
Associated With myf6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002546 Myogenic muscle-specific protein, N-terminal
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR039704 Myogenic factor
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Myogenic factor Myogenic muscle-specific protein, N-terminal
UniProtKB:B3DK75 InterPro 239
UniProtKB:Q6VNZ9 InterPro 239
UniProtKB:A0AC58J627 InterPro 284
UniProtKB:A0AC58J629 InterPro 284
UniProtKB:A0AC58J632 InterPro 126
UniProtKB:A0AC58J634 InterPro 284
UniProtKB:A0AC58J637 InterPro 126
UniProtKB:A0AC58J638 InterPro 126
UniProtKB:A0AC58J640 InterPro 284
UniProtKB:A0AC58J642 InterPro 126
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA myf6-201 (1)
Ensembl
Ensembl 720 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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