Gene
vegfc
- ID
- ZDB-GENE-040303-4
- Name
- vascular endothelial growth factor c
- Symbol
- vegfc Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Exhibits vascular endothelial growth factor receptor binding activity. Involved in several processes, including motor neuron axon guidance; transmembrane receptor protein tyrosine kinase signaling pathway; and vasculature development. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Is expressed in several structures, including blood vessel; brain; hypochord; nucleate erythrocyte; and trunk. Orthologous to human VEGFC (vascular endothelial growth factor C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 45 figures from 37 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu252 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 39 figures from 21 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary lymphedema ID | Alliance | Lymphatic malformation 4 | 615907 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CXCXC repeat | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived/Vascular endothelial growth factor |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7T3I6
|
396 | |||||
|
UniProtKB:A0A8M9PHS0
|
277 | |||||
|
UniProtKB:A0A8M2B6U8
|
395 | |||||
|
UniProtKB:A0A8M9PC47
|
339 |
Interactions and Pathways
No data available
Plasmids
No data available