Gene

gnmt

ID
ZDB-GENE-040227-1
Name
glycine N-methyltransferase
Symbol
gnmt Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have several functions, including S-adenosyl-L-methionine binding activity; glycine N-methyltransferase activity; and glycine binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to localize to cytosol. Is expressed in spinal cord. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase).
Genome Resources
Note
None
Expression
All Expression Data
from Newman et al., 2009
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnmt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
glycine N-methyltransferase deficiency Alliance Glycine N-methyltransferase deficiency 606664
Associated With gnmt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR025714 Methyltransferase domain
Family IPR014369 Glycine/Sarcosine N-methyltransferase
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Domain Details Per Protein
Protein Length Glycine/Sarcosine N-methyltransferase Methyltransferase domain S-adenosyl-L-methionine-dependent methyltransferase
UniProtKB:Q6P607 294
UniProtKB:F1Q884 294
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations