Gene
gnmt
- ID
- ZDB-GENE-040227-1
- Name
- glycine N-methyltransferase
- Symbol
- gnmt Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have several functions, including S-adenosyl-L-methionine binding activity; glycine N-methyltransferase activity; and glycine binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Is expressed in spinal cord. Orthologous to human GNMT (glycine N-methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycine N-methyltransferase deficiency | Alliance | Glycine N-methyltransferase deficiency | 606664 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycine/Sarcosine N-methyltransferase | Methyltransferase domain | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6P607
|
294 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available