Gene
rab5ab
- ID
- ZDB-GENE-040122-3
- Name
- RAB5A, member RAS oncogene family, b
- Symbol
- rab5ab Nomenclature History
- Previous Names
-
- rab5al
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity. Acts upstream of or within several processes, including Spemann organizer formation; epiboly involved in gastrulation with mouth forming second; and nodal signaling pathway. Predicted to be located in early endosome membrane and plasma membrane. Predicted to be active in axon and postsynaptic early endosome. Orthologous to human RAB5A (RAB5A, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138917 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kenyon et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
| UniProtKB:Q7ZUG4 | InterPro | 216 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rab5ab-201
(1)
|
Ensembl | 1,279 nt | ||
| mRNA |
rab5ab-202
(1)
|
Ensembl | 823 nt |
Interactions and Pathways
No data available
Plasmids