ZFIN ID: ZDB-GENE-040115-4
Gene Name: profilin 2
Gene Symbol: pfn2    Nomenclature History

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Previous Names: wu:fb01g08, wu:fb54f09, wu:fd58f06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly and regulation of actin filament polymerization. Predicted to localize to cytoplasm. Is expressed in artery; axial vasculature; and vein. Orthologous to human PFN2 (profilin 2).
Genome Resources: Alliance (1),  Gene:394235 (1),  Ensembl(GRCz11):ENSDARG00000003952 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 5 figures (3 images) from Thisse et al., 2004 [IMAGE:7151596]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-pfn2 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pfn2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pfn2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process actin cytoskeleton organization (more)
Cellular Component cytoplasm (more)
Molecular Function actin binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pfn2-201 (1)    Ensembl 2887
pfn2-202 (1)    Ensembl 920
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pfn2 No data available
MARKER RELATIONSHIPS
pfn2 Contained in: [BAC] CH73-107C10 (1), DKEY-250M6 (1) (order this)
pfn2 Encodes: [EST] fb01g08 (1), fb54f09 (1), fd58f06 (1), IMAGE:7151596 (1)
[cDNA] MGC:55402 (1), MGC:77530 (1), MGC:191917 (1)
pfn2 Has Artifact: [cDNA] MGC:173905
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_201336 (1) 2850 nt
Genomic GenBank:CR925810 (1) 197451 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IPL1 (1) 140 aa
Sequence Information (all 26)
ORTHOLOGY for pfn2 ( Chr: 22 )
CITATIONS (26)