Gene
cyp4t8
- ID
- ZDB-GENE-031219-3
- Name
- cytochrome P450, family 4, subfamily T, polypeptide 8
- Symbol
- cyp4t8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be located in endoplasmic reticulum membrane. Is expressed in myotome; nervous system; otic vesicle; pharyngeal arch 3-7 skeleton; and somite. Human ortholog(s) of this gene implicated in hypertension. Orthologous to several human genes including CYP4B1 (cytochrome P450 family 4 subfamily B member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1041 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 Monooxygenases | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6PH32
|
458 | |||||
|
UniProtKB:E7FB64
|
509 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp4t8-201
(1)
|
Ensembl | 1,808 nt | ||
| mRNA |
cyp4t8-202
(1)
|
Ensembl | 1,811 nt | ||
| ncRNA |
cyp4t8-003
(1)
|
Ensembl | 653 nt |
Interactions and Pathways
No data available
Plasmids
No data available