Gene

fhl1b

ID
ZDB-GENE-031219-1
Name
four and a half LIM domains 1b
Symbol
fhl1b Nomenclature History
Previous Names
  • fhl
  • cb1039 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Is predicted to enable transmembrane transporter binding activity. Acts upstream of or within animal organ development; calcium ion homeostasis; and locomotory behavior. Is expressed in several structures, including cardiovascular system; digestive system; hypochord; liver primordium; and musculature system. Human ortholog(s) of this gene implicated in Uruguay faciocardiomusculoskeletal syndrome; X-linked Emery-Dreifuss muscular dystrophy 6; reducing body myopathy 1A; and reducing body myopathy 1B. Orthologous to human FHL1 (four and a half LIM domains 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fhl1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
reducing body myopathy 1A Alliance Reducing body myopathy, X-linked 1a, severe, infantile or early childhood onset 300717
reducing body myopathy 1B Alliance Reducing body myopathy, X-linked 1b, with late childhood or adult onset 300718
scapuloperoneal myopathy Alliance Scapuloperoneal myopathy, X-linked dominant 300695
Uruguay faciocardiomusculoskeletal syndrome Alliance ?Uruguay faciocardiomusculoskeletal syndrome 300280
X-linked Emery-Dreifuss muscular dystrophy 6 Alliance Emery-Dreifuss muscular dystrophy 6, X-linked 300696
X-linked Emery-Dreifuss muscular dystrophy 6 Alliance Myopathy, X-linked, with postural muscle atrophy 300696
Associated With fhl1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001781 Zinc finger, LIM-type
Family IPR037987 Four and a half LIM domains protein 2/3/5
Domain Details Per Protein
Protein Length Four and a half LIM domains protein 2/3/5 Zinc finger, LIM-type
UniProtKB:F1Q7A2 280
UniProtKB:Q7T327 280
UniProtKB:B0JZK9 280
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations