cwf19l1

ID

ZDB-GENE-031204-5

Name

CWF19 like cell cycle control factor 1

Symbol

cwf19l1 Nomenclature History

Previous Names

sb:cb1004
si:ch211-234f20.6
zgc:153338

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable RNA lariat debranching enzyme activator activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. Is expressed in blood. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 17. Orthologous to human CWF19L1 (CWF19 like cell cycle control factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb1004 (6 images)
IMAGE:6907342 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Burns et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cwf19l1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 17	Alliance	Spinocerebellar ataxia, autosomal recessive 17	616127

Associated With cwf19l1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006767	Cwf19-like protein, C-terminal domain-2
Domain	IPR006768	Cwf19-like, C-terminal domain-1
Family	IPR040194	Cwf19-like protein
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like
Homologous_superfamily	IPR036265	HIT-like superfamily