Gene

gbgt1l4

ID

ZDB-GENE-031204-4

Name

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4

Symbol

gbgt1l4 Nomenclature History

Previous Names

FS-L4 (1)
alpha 1,3-galctosyltransferase (1)
sb:cb1003
zgc:66417

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable glycosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and vesicle. Is expressed in several structures, including EVL; ectoderm; epidermis; pectoral fin musculature; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; graft-versus-host disease; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to several human genes including GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb1003 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gbgt1l4 Human Ortholog

No data available

Associated With gbgt1l4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR005076	Glycosyl transferase, family 6
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M2BCB7	InterPro	343
UniProtKB:Q7SXD8	InterPro	349
UniProtKB:A2CED5	InterPro	342

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gbgt1l4-201 (1) Ensembl	Ensembl	1,591 nt	Select Tool ZFIN BLAST
mRNA	gbgt1l4-202 (1) Ensembl	Ensembl	949 nt	Select Tool ZFIN BLAST
mRNA	gbgt1l4-203 (1) Ensembl	Ensembl	1,671 nt	Select Tool ZFIN BLAST
ncRNA	gbgt1l4-004 (1) Ensembl	Ensembl	828 nt	Select Tool ZFIN BLAST
ncRNA	gbgt1l4-005 (1) Ensembl	Ensembl	409 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations