Gene
pkma
- ID
- ZDB-GENE-031201-4
- Name
- pyruvate kinase M1/2a
- Symbol
- pkma Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have pyruvate kinase activity. Predicted to be involved in cellular response to insulin stimulus and glycolytic process. Predicted to localize to cytoplasm. Is expressed in several structures, including nervous system; neural tube; otic vesicle; pericardial region; and solid lens vesicle. Orthologous to human PKM (pyruvate kinase M1/2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1029 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Stone et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018209 | Pyruvate kinase, active site |
| Domain | IPR015793 | Pyruvate kinase, barrel |
| Domain | IPR015795 | Pyruvate kinase, C-terminal |
| Family | IPR001697 | Pyruvate kinase |
| Homologous_superfamily | IPR011037 | Pyruvate kinase-like, insert domain superfamily |
| Homologous_superfamily | IPR015806 | Pyruvate kinase, insert domain superfamily |
| Homologous_superfamily | IPR015813 | Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily |
| Homologous_superfamily | IPR036918 | Pyruvate kinase, C-terminal domain superfamily |
| Homologous_superfamily | IPR040442 | Pyruvate kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Pyruvate kinase | Pyruvate kinase, active site | Pyruvate kinase, barrel | Pyruvate kinase, C-terminal | Pyruvate kinase, C-terminal domain superfamily | Pyruvate kinase, insert domain superfamily | Pyruvate kinase-like domain superfamily | Pyruvate kinase-like, insert domain superfamily | Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVT2
|
532 | |||||||||
|
UniProtKB:A0A0R4IGP6
|
532 |
Interactions and Pathways
No data available
Plasmids
No data available