Gene
pkma
- ID
- ZDB-GENE-031201-4
- Name
- pyruvate kinase M1/2a
- Symbol
- pkma Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable pyruvate kinase activity. Involved in sprouting angiogenesis. Predicted to be active in cytoplasm. Is expressed in several structures, including nervous system; neural tube; otic vesicle; pericardial region; and solid lens vesicle. Orthologous to human PKM (pyruvate kinase M1/2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1029 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Stone et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018209 | Pyruvate kinase, active site |
| Domain | IPR015793 | Pyruvate kinase, barrel |
| Domain | IPR015795 | Pyruvate kinase, C-terminal |
| Family | IPR001697 | Pyruvate kinase |
| Homologous_superfamily | IPR011037 | Pyruvate kinase-like, insert domain superfamily |
| Homologous_superfamily | IPR015806 | Pyruvate kinase, insert domain superfamily |
| Homologous_superfamily | IPR015813 | Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily |
| Homologous_superfamily | IPR036918 | Pyruvate kinase, C-terminal domain superfamily |
| Homologous_superfamily | IPR040442 | Pyruvate kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Pyruvate kinase | Pyruvate kinase, active site | Pyruvate kinase, barrel | Pyruvate kinase, C-terminal | Pyruvate kinase, C-terminal domain superfamily | Pyruvate kinase, insert domain superfamily | Pyruvate kinase-like domain superfamily | Pyruvate kinase-like, insert domain superfamily | Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVT2
|
532 | |||||||||
|
UniProtKB:A0A0R4IGP6
|
532 |
Interactions and Pathways
No data available
Plasmids
No data available