Gene
hipk2
- ID
- ZDB-GENE-031125-4
- Name
- homeodomain interacting protein kinase 2
- Symbol
- hipk2 Nomenclature History
- Previous Names
-
- cb1009 (1)
- si:dkey-16j24.2
- wu:fk56d12
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable SMAD binding activity; protein kinase activity; and transcription corepressor activity. Predicted to contribute to transcription coactivator activity. Acts upstream of or within convergent extension and regulation of melanocyte differentiation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with PML body. Is expressed in notochord. Orthologous to human HIPK2 (homeodomain interacting protein kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1009 (11 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR050494 | Serine/threonine and dual-specificity kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine and dual-specificity kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B5G3 | InterPro | 1197 | |||||
| UniProtKB:F1Q4N0 | InterPro | 1228 | |||||
| UniProtKB:A0A8M2B5J6 | InterPro | 1227 | |||||
| UniProtKB:A0A8M2B5G0 | InterPro | 1196 |
Interactions and Pathways
No data available
Plasmids
No data available