Gene

hipk2

ID

ZDB-GENE-031125-4

Name

homeodomain interacting protein kinase 2

Symbol

hipk2 Nomenclature History

Previous Names

cb1009 (1)
si:dkey-16j24.2
wu:fk56d12

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to contribute to transcription coactivator activity. Involved in convergent extension and regulation of melanocyte differentiation. Predicted to colocalize with PML body. Is expressed in notochord. Orthologous to human HIPK2 (homeodomain interacting protein kinase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb1009 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hipk2 Human Ortholog

No data available

Associated With hipk2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:S6BAK9 InterPro	1231
UniProtKB:Q1MTA8 InterPro	1220
UniProtKB:B7ZVU1 InterPro	1223
UniProtKB:A0A2R8QNB7 InterPro	1224
UniProtKB:Q1LUH8 InterPro	1226
UniProtKB:F1Q4N0 InterPro	1228