Gene

hipk2

ID
ZDB-GENE-031125-4
Name
homeodomain interacting protein kinase 2
Symbol
hipk2 Nomenclature History
Previous Names
  • cb1009 (1)
  • si:dkey-16j24.2
  • wu:fk56d12
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable SMAD binding activity; protein kinase activity; and transcription corepressor activity. Predicted to contribute to transcription coactivator activity. Acts upstream of or within convergent extension and regulation of melanocyte differentiation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with PML body. Is expressed in notochord. Orthologous to human HIPK2 (homeodomain interacting protein kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hipk2 Human Ortholog
No data available
Associated With hipk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:S6BAK9 1231
UniProtKB:F1Q4N0 1228
UniProtKB:Q1LUH8 1226
UniProtKB:A0A2R8QNB7 1224
UniProtKB:B7ZVU1 1223
UniProtKB:Q1MTA8 1220
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations