Gene
supt16h
- ID
- ZDB-GENE-031118-96
- Name
- SPT16 homolog, facilitates chromatin remodeling subunit
- Symbol
- supt16h Nomenclature History
- Previous Names
-
- spt16 (1)
- fq44d08
- wu:fq44d08
- zgc:194708
- zgc:194732
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have nucleosome binding activity. Predicted to be involved in DNA replication-independent nucleosome organization; positive regulation of transcription elongation from RNA polymerase II promoter; and transcription elongation from RNA polymerase II promoter. Predicted to localize to FACT complex. Orthologous to human SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Espanola et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Espanola et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with dysmorphic facies and thin corpus callosum | Alliance | Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum | 619480 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000994 | Peptidase M24 |
| Domain | IPR013719 | Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain |
| Domain | IPR013953 | FACT complex subunit Spt16 domain |
| Domain | IPR029148 | FACT complex subunit Spt16, N-terminal lobe domain |
| Domain | IPR033825 | FACT complex subunit Spt16, peptidase M24-like domain |
| Domain | IPR048969 | FACT complex subunit SPT16, C-terminal domain |
| Family | IPR040258 | FACT complex subunit Spt16 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029149 | Creatinase/Aminopeptidase P/Spt16, N-terminal |
| Homologous_superfamily | IPR036005 | Creatinase/aminopeptidase-like |
Domain Details Per Protein
| Protein | Length | Creatinase/aminopeptidase-like | Creatinase/Aminopeptidase P/Spt16, N-terminal | FACT complex subunit Spt16 | FACT complex subunit SPT16, C-terminal domain | FACT complex subunit Spt16 domain | FACT complex subunit Spt16, N-terminal lobe domain | FACT complex subunit Spt16, peptidase M24-like domain | Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain | Peptidase M24 | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5A4L9
|
1033 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
supt16h-201
(1)
|
Ensembl | 8,455 nt | ||
| mRNA |
supt16h-202
(1)
|
Ensembl | 3,917 nt | ||
| mRNA |
supt16h-203
(1)
|
Ensembl | 8,455 nt | ||
| mRNA |
supt16h-204
(1)
|
Ensembl | 195 nt |
Interactions and Pathways
No data available
Plasmids
No data available