Gene

supt16h

ID
ZDB-GENE-031118-96
Name
SPT16 homolog, facilitates chromatin remodeling subunit
Symbol
supt16h Nomenclature History
Previous Names
  • spt16 (1)
  • fq44d08
  • wu:fq44d08
  • zgc:194708
  • zgc:194732
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have nucleosome binding activity. Predicted to be involved in DNA replication-independent nucleosome organization; positive regulation of transcription elongation from RNA polymerase II promoter; and transcription elongation from RNA polymerase II promoter. Predicted to localize to FACT complex. Orthologous to human SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Espanola et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from Espanola et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With supt16h Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neurodevelopmental disorder with dysmorphic facies and thin corpus callosum Alliance Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum 619480
Associated With supt16h Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000994 Peptidase M24
Domain IPR013719 Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain
Domain IPR013953 FACT complex subunit Spt16 domain
Domain IPR029148 FACT complex subunit Spt16, N-terminal lobe domain
Domain IPR033825 FACT complex subunit Spt16, peptidase M24-like domain
Family IPR040258 FACT complex subunit Spt16
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal
Homologous_superfamily IPR036005 Creatinase/aminopeptidase-like
Domain Details Per Protein
Protein Length Creatinase/aminopeptidase-like Creatinase/Aminopeptidase P/Spt16, N-terminal FACT complex subunit Spt16 FACT complex subunit Spt16 domain FACT complex subunit Spt16, N-terminal lobe domain FACT complex subunit Spt16, peptidase M24-like domain Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain Peptidase M24 PH-like domain superfamily
UniProtKB:A5A4L9 1033
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations