Gene
aco1
- ID
- ZDB-GENE-031118-76
- Name
- aconitase 1, soluble
- Symbol
- aco1 Nomenclature History
- Previous Names
-
- IRP1 (1)
- wu:fo75b03
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have aconitate hydratase activity; iron-responsive element binding activity; and iron-sulfur cluster binding activity. Predicted to be involved in citrate metabolic process and tricarboxylic acid cycle. Predicted to localize to cytosol and mitochondrion. Is expressed in blood and presumptive blood. Orthologous to human ACO1 (aconitase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Haunhorst et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018136 | Aconitase family, 4Fe-4S cluster binding site |
| Domain | IPR000573 | Aconitase A/isopropylmalate dehydratase small subunit, swivel domain |
| Domain | IPR001030 | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain |
| Domain | IPR044137 | Aconitase A, swivel domain |
| Family | IPR006249 | Aconitase/Iron-responsive element-binding protein 2 |
| Homologous_superfamily | IPR015928 | Aconitase/3-isopropylmalate dehydratase, swivel |
| Homologous_superfamily | IPR015931 | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 |
| Homologous_superfamily | IPR036008 | Aconitase, iron-sulfur domain |
Domain Details Per Protein
| Protein | Length | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 | Aconitase/3-isopropylmalate dehydratase, swivel | Aconitase A/isopropylmalate dehydratase small subunit, swivel domain | Aconitase A, swivel domain | Aconitase family, 4Fe-4S cluster binding site | Aconitase/Iron-responsive element-binding protein 2 | Aconitase, iron-sulfur domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q3YMK9
|
890 | ||||||||
|
UniProtKB:F1QM42
|
890 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available