Gene

dscamb

ID

ZDB-GENE-031118-67

Name

Down syndrome cell adhesion molecule b

Symbol

dscamb Nomenclature History

Previous Names

fm10g02
si:ch211-69g13.1 (1)
wu:fm10g02

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within enteric nervous system development. Predicted to be located in membrane and synapse. Predicted to be active in axon; neuronal cell body; and plasma membrane. Is expressed in central nervous system; intestinal bulb; and retina. Orthologous to human DSCAM (DS cell adhesion molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dscamb Human Ortholog

No data available

Associated With dscamb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR013106	Immunoglobulin V-set domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin domain subtype	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Immunoglobulin V-set domain
UniProtKB:A0A8M3AIA2	InterPro	2018
UniProtKB:F1Q4W9	InterPro	2020

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	dscamb-201 (1) Ensembl	Ensembl		6,063 nt	Select Tool ZFIN BLAST
mRNA	dscamb-202 (1) Ensembl	Ensembl		6,992 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations