Gene
cstf2
- ID
- ZDB-GENE-031118-2
- Name
- cleavage stimulation factor, 3' pre-RNA, subunit 2
- Symbol
- cstf2 Nomenclature History
- Previous Names
-
- CstF-64 (1)
- fb11e07
- wu:fb11e07
- zgc:77730
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable mRNA binding activity. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human CSTF2 (cleavage stimulation factor subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56346 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Intellectual developmental disorder, X-linked 113 | 301116 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR025742 | Cleavage stimulation factor subunit 2, hinge domain |
| Domain | IPR026896 | Transcription termination and cleavage factor, C-terminal domain |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR038192 | Transcription termination and cleavage factor, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cleavage stimulation factor subunit 2, hinge domain | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | Transcription termination and cleavage factor, C-terminal domain | Transcription termination and cleavage factor, C-terminal domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4I9I2 | InterPro | 508 | ||||||
| UniProtKB:Q6P0U7 | InterPro | 488 |
Interactions and Pathways
No data available
Plasmids
No data available