Gene

dnajb11

ID

ZDB-GENE-031113-9

Name

DnaJ heat shock protein family (Hsp40) member B11

Symbol

dnajb11 Nomenclature History

Previous Names

cb954 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have unfolded protein binding activity. Predicted to be involved in protein folding. Human ortholog(s) of this gene implicated in polycystic kidney disease. Is expressed in several structures, including axial mesoderm; blood vessel; nervous system; neural tube; and pectoral fin. Orthologous to human DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb954 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dnajb11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
polycystic kidney disease 6	Alliance	Polycystic kidney disease 6 with or without polycystic liver disease	618061

Associated With dnajb11 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018253	DnaJ domain, conserved site
Domain	IPR001623	DnaJ domain
Domain	IPR002939	Chaperone DnaJ, C-terminal
Family	IPR051736	DnaJ homolog subfamily B member 11-like
Homologous_superfamily	IPR008971	HSP40/DnaJ peptide-binding
Homologous_superfamily	IPR036869	Chaperone J-domain superfamily