Gene
emx1
- ID
- ZDB-GENE-031007-7
- Name
- empty spiracles homeobox 1
- Symbol
- emx1 Nomenclature History
- Previous Names
-
- zgc:101821
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in pronephric distal tubule development. Predicted to localize to nucleus. Is expressed in several structures, including forebrain; forebrain neural keel; neural plate; presumptive telencephalon; and pronephros. Orthologous to human EMX1 (empty spiracles homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 67 figures from 50 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000047 | Helix-turn-helix motif |
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR020479 | Homeodomain, metazoa |
| Family | IPR050877 | EMX/VAX/Noto Homeobox Transcription Factors |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Length | EMX/VAX/Noto Homeobox Transcription Factors | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A3KNV6
|
231 | ||||||
|
UniProtKB:Q804S6
|
231 |
Interactions and Pathways
No data available
Plasmids
No data available