Gene

sirt6

ID
ZDB-GENE-031007-2
Name
sirtuin 6
Symbol
sirt6 Nomenclature History
Previous Names
  • zgc:86729
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have NAD+ binding activity. Is expressed in liver and retina. Orthologous to human SIRT6 (sirtuin 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sirt6 Human Ortholog
No data available
Associated With sirt6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR026590 Sirtuin family, catalytic core domain
Family IPR003000 Sirtuin family
Family IPR050134 NAD-dependent sirtuin protein deacylases
Homologous_superfamily IPR029035 DHS-like NAD/FAD-binding domain superfamily
Domain Details Per Protein
Protein Length DHS-like NAD/FAD-binding domain superfamily NAD-dependent sirtuin protein deacylases Sirtuin family Sirtuin family, catalytic core domain
UniProtKB:A0A8M9Q7D3 354
UniProtKB:Q6IQK0 354
UniProtKB:A0A8M9QD86 308
UniProtKB:A0A8M9PV38 282
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sirt6-201 (1) Ensembl 1,418 nt
mRNA sirt6-202 (1) Ensembl 1,418 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations