Gene
sirt6
- ID
- ZDB-GENE-031007-2
- Name
- sirtuin 6
- Symbol
- sirt6 Nomenclature History
- Previous Names
-
- zgc:86729
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable histone H3K9 deacetylase activity, NAD-dependent and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome, telomeric region and endoplasmic reticulum. Predicted to be active in nucleus. Is expressed in liver and retina. Orthologous to human SIRT6 (sirtuin 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897658 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | DHS-like NAD/FAD-binding domain superfamily | NAD-dependent sirtuin protein deacylases | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q7D3 | InterPro | 354 | ||||
| UniProtKB:Q6IQK0 | InterPro | 354 | ||||
| UniProtKB:A0A8M9QD86 | InterPro | 308 | ||||
| UniProtKB:A0A8M9PV38 | InterPro | 282 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available