Gene
nt5c2l1
- ID
- ZDB-GENE-031006-8
- Name
- 5'-nucleotidase, cytosolic II, like 1
- Symbol
- nt5c2l1 Nomenclature History
- Previous Names
-
- nt5c2
- cb904 (1)
- id:ibd5113
- zgc:92102
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable 5'-nucleotidase activity. Acts upstream of or within cellular response to xenobiotic stimulus. Is expressed in blood; eye; tail bud; ventral mesoderm; and yolk syncytial layer. Orthologous to human NT5DC4 (5'-nucleotidase domain containing 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb904 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9485 | Allele with one point mutation | Unknown | Splice Site | ENU |
1 - 1 of 1
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | HAD-like superfamily | HAD superfamily | HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase | Purine 5'-nucleotidase |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PTI8 | InterPro | 546 | ||||
| UniProtKB:A0A8M9QGL3 | InterPro | 547 | ||||
| UniProtKB:Q66I11 | InterPro | 518 |
1 - 3 of 3
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nt5c2l1-201
(1)
|
Ensembl | 2,250 nt | ||
| mRNA |
nt5c2l1-202
(1)
|
Ensembl | 2,218 nt | ||
| mRNA |
nt5c2l1-204
(1)
|
Ensembl | 717 nt | ||
| ncRNA |
nt5c2l1-003
(1)
|
Ensembl | 841 nt |
1 - 4 of 4
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-76P7 | ZFIN Curated Data | |
| Contains | STS | chunp30589 | ||
| Encodes | EST | cb904 | Thisse et al., 2001 | |
| Encodes | EST | ibd5113 | ||
| Encodes | cDNA | MGC:92102 | ZFIN Curated Data |
1 - 5 of 5
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001004549 (1) | 2267 nt | ||
| Genomic | GenBank:BX927385 (1) | 243665 nt | ||
| Polypeptide | UniProtKB:A0A8M9QGL3 (1) | 547 aa |
No data available
- Wang, G., Zhang, G., Li, Z., Fawcett, C.H., Coble, M., Sosa, M.X., Tsai, T., Malesky, K., Thibodeaux, S.J., Zhu, P., Glass, D.J., Fishman, M.C. (2019) Abnormal Behavior of Zebrafish Mutant in Dopamine Transporter Is Rescued by Clozapine. iScience. 17:325-333
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Lam, S.H., Mathavan, S., Tong, Y., Li, H., Karuturi, R.K., Wu, Y., Vega, V.B., Liu, E.T., and Gong, Z. (2008) Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. PLoS Genetics. 4(7):e1000121
- Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 5 of 5
Show