Gene
idh1
- ID
- ZDB-GENE-031006-1
- Name
- isocitrate dehydrogenase (NADP(+)) 1
- Symbol
- idh1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable isocitrate dehydrogenase (NADP+) activity. Acts upstream of or within hemopoiesis. Predicted to be active in cytosol; mitochondrion; and peroxisome. Is expressed in several structures, including digestive system; ectoderm; mesoderm; nervous system; and pronephric duct. Human ortholog(s) of this gene implicated in autoimmune disease; hematologic cancer (multiple); hepatocellular clear cell carcinoma; and high grade glioma (multiple). Orthologous to human IDH1 (isocitrate dehydrogenase (NADP(+)) 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb876 (20 images)
- IMAGE:7143416 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shi et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Glioma, susceptibility to, somatic} | 137800 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Isocitrate dehydrogenase NADP-dependent | Isocitrate/isopropylmalate dehydrogenase, conserved site | Isopropylmalate dehydrogenase-like domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BF40 | InterPro | 415 | |||
| UniProtKB:Q802Y2 | InterPro | 429 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available