Gene
pdia3
- ID
- ZDB-GENE-031002-9
- Name
- protein disulfide isomerase family A, member 3
- Symbol
- pdia3 Nomenclature History
- Previous Names
-
- erp57 (1)
- sb:cb825
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to localize to cell surface and endoplasmic reticulum. Human ortholog(s) of this gene implicated in autoimmune hepatitis. Is expressed in several structures, including axis; hatching gland; hypochord; nervous system; and pleuroperitoneal region. Orthologous to human PDIA3 (protein disulfide isomerase family A member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb825 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017937 | Thioredoxin, conserved site |
| Domain | IPR005788 | Protein disulfide-isomerase, thioredoxin-like domain |
| Domain | IPR013766 | Thioredoxin domain |
| Domain | IPR041868 | Protein disulfide-isomerase A3, first redox inactive TRX-like domain b |
| Family | IPR005792 | Protein disulphide isomerase |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Protein disulfide-isomerase A3, first redox inactive TRX-like domain b | Protein disulfide-isomerase, thioredoxin-like domain | Protein disulphide isomerase | Thioredoxin, conserved site | Thioredoxin domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1NXI0
|
494 |
Interactions and Pathways
No data available
Plasmids
No data available