Gene

pdia3

ID
ZDB-GENE-031002-9
Name
protein disulfide isomerase family A, member 3
Symbol
pdia3 Nomenclature History
Previous Names
  • erp57 (1)
  • sb:cb825
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to localize to cell surface and endoplasmic reticulum. Human ortholog(s) of this gene implicated in autoimmune hepatitis. Is expressed in several structures, including axis; hatching gland; hypochord; nervous system; and pleuroperitoneal region. Orthologous to human PDIA3 (protein disulfide isomerase family A member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdia3 Human Ortholog
No data available
Associated With pdia3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017937 Thioredoxin, conserved site
Domain IPR005788 Disulphide isomerase
Domain IPR013766 Thioredoxin domain
Domain IPR041868 Protein disulfide-isomerase A3, first redox inactive TRX-like domain b
Family IPR005792 Protein disulphide isomerase
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Disulphide isomerase Protein disulfide-isomerase A3, first redox inactive TRX-like domain b Protein disulphide isomerase Thioredoxin, conserved site Thioredoxin domain Thioredoxin-like superfamily
UniProtKB:A0A0R4IBZ3 90
UniProtKB:Q803D7 492
UniProtKB:A0A0R4IGN3 459
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations