Gene

fam49a

ID
ZDB-GENE-031002-50
Name
family with sequence similarity 49 member A
Symbol
fam49a Nomenclature History
Previous Names
  • fam49ab (1)
  • sb:cb866
  • si:ch211-223o11.1
  • si:ch211-89p3.1
  • zgc:55309
  • znf395
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in regulation of T cell differentiation and thymus development. Is expressed in several structures, including adaxial cell; digestive system; musculature system; sensory system; and trunk. Orthologous to human CYRIA (CYFIP related Rac1 interactor A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Li et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fam49a Human Ortholog
No data available
Associated With fam49a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009828 CYRIA/CYRIB, Rac1 binding domain
Family IPR039789 CYFIP-related Rac1 interactor
Domain Details Per Protein
Protein Length CYFIP-related Rac1 interactor CYRIA/CYRIB, Rac1 binding domain
UniProtKB:A0A0R4IMR9 381
UniProtKB:A0A8M2B7R9 324
UniProtKB:Q7ZW35 323
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fam49a-201 (1) Ensembl 1,851 nt
mRNA fam49a-203 (1) Ensembl 1,850 nt
mRNA fam49a-206 (1) Ensembl 889 nt
mRNA fam49a-208 (1) Ensembl 1,854 nt
mRNA fam49a-209 (1) Ensembl 1,668 nt
ncRNA znf395-003 (1) Ensembl 302 nt
ncRNA znf395-004 (1) Ensembl 892 nt
ncRNA znf395-006 (1) Ensembl 738 nt
ncRNA znf395-007 (1) Ensembl 729 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations