Gene
sh3gl1b
- ID
- ZDB-GENE-031001-6
- Name
- SH3-domain GRB2-like 1b
- Symbol
- sh3gl1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be located in cell projection; early endosome membrane; and podosome. Predicted to be active in cytoplasm; glutamatergic synapse; and presynapse. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; nervous system; and neural tube. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb831 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acute myeloid leukemia | Alliance | Leukemia, acute myeloid | 601626 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | BAR domain | Endophilin-A, SH3 domain | Endophilin/SH3RF | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IGE6 | InterPro | 367 | ||||||
| UniProtKB:A0A8M3BBQ5 | InterPro | 366 | ||||||
| UniProtKB:A0A8M2BE91 | InterPro | 350 | ||||||
| UniProtKB:Q7ZVA3 | InterPro | 351 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sh3gl1b-201
(1)
|
Ensembl | 1,776 nt | ||
| mRNA |
sh3gl1b-202
(1)
|
Ensembl | 1,953 nt |
Interactions and Pathways
No data available
Plasmids
No data available