ZFIN is now using GRCz12tu for Genomic Data
Gene
aaas
- ID
- ZDB-GENE-030912-4
- Name
- aladin WD repeat nucleoporin
- Symbol
- aaas Nomenclature History
- Previous Names
-
- zgc:85873
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in microtubule bundle formation and mitotic spindle assembly. Predicted to be part of nuclear pore. Is expressed in head. Human ortholog(s) of this gene implicated in achalasia and triple-A syndrome. Orthologous to human AAAS (aladin WD repeat nucleoporin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907703 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| triple-A syndrome | Alliance | Achalasia-addisonianism-alacrimia syndrome | 231550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Aladin | Aladin, seven-bladed propeller | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NW98 | InterPro | 499 | |||||
| UniProtKB:A0AB32U053 | InterPro | 500 | |||||
| UniProtKB:A0AC58GDP8 | InterPro | 399 | |||||
| UniProtKB:A0AC58GDQ1 | InterPro | 500 | |||||
| UniProtKB:A0AC58GDQ4 | InterPro | 500 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers