Gene
rdh1
- ID
- ZDB-GENE-030912-15
- Name
- retinol dehydrogenase 1
- Symbol
- rdh1 Nomenclature History
- Previous Names
-
- RDHB (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within several processes, including embryonic pectoral fin morphogenesis; exocrine pancreas development; and retinoid metabolic process. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in intestinal bulb and liver. Human ortholog(s) of this gene implicated in fundus albipunctatus and night blindness. Orthologous to human HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6) and RDH5 (retinol dehydrogenase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56342 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NAD(P)-binding domain superfamily | Short-chain dehydrogenase/reductase SDR |
|---|---|---|---|
|
UniProtKB:Q7ZUX4
|
327 | ||
|
UniProtKB:A0A286Y8B5
|
327 |
Interactions and Pathways
No data available
Plasmids
No data available