Gene

hnrnpa1b

ID
ZDB-GENE-030912-14
Name
heterogeneous nuclear ribonucleoprotein A1b
Symbol
hnrnpa1b Nomenclature History
Previous Names
  • hnrnpa1
  • hnrpa1 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; gut; retina; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to human HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hnrnpa1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis type 20 Alliance Amyotrophic lateral sclerosis 20 615426
inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3 Alliance ?Inclusion body myopathy with early-onset Paget disease without frontotemporal dementia 3 615424
Associated With hnrnpa1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034803 hnRNP A1, RNA recognition motif 2
Family IPR021662 Nuclear factor hnRNPA1
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length hnRNP A1, RNA recognition motif 2 Nuclear factor hnRNPA1 Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:F1R4I4 120
UniProtKB:F1R2T6 65
UniProtKB:F1QS20 281
UniProtKB:F1QFV2 403
UniProtKB:Q803K3 422
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations