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ZIRC
ZFIN ID: ZDB-GENE-030909-6
Gene Name: minichromosome maintenance complex component 6
Gene Symbol: mcm6    Nomenclature History

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Previous Names: MCM6z (1), cb800 (1), im:7140796, wu:fb30d05, wu:fc26f09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to contribute to single-stranded 3'-5' DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and double-strand break repair via break-induced replication. Predicted to localize to the MCM complex and nucleus. Is expressed in central nervous system and proliferative region. Orthologous to human MCM6 (minichromosome maintenance complex component 6).
Genome Resources: Alliance (1),  Gene:566409 (1),  Ensembl(GRCz11):ENSDARG00000057683 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 5 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2001 [cb800]
  6 figures (11 images) from Thisse et al., 2004 [IMAGE:7140796]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38542 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mcm6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    lactose intolerance Alliance Lactase persistence/nonpersistence 223100
    DISEASE ASSOCIATED WITH mcm6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA replication (more)
    Cellular Component MCM complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mcm6-201 (1)    Ensembl 3218
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mcm6 No data available
    MARKER RELATIONSHIPS
    mcm6 Contained in: [BAC] CH73-71C20 (1) (order this)
    mcm6 Encodes: [EST] cb800 (1) (order this), fb30d05, fc26f09, IMAGE:7055439, IMAGE:7140796 (1) (order this)
    [cDNA] MGC:158377 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001082849 (1) 3259 bp
    Genomic GenBank:CU639421 (1) 105459 bp
    Select Tool
    Polypeptide UniProtKB:A0A0E4AXB8 (1) 830 aa
    Sequence Clusters UniGene:33010 (1)
    Sequence Information (all 19)
    ORTHOLOGY for mcm6 ( Chr: 6 )
    CITATIONS (31)