Gene

gtpbp1

ID
ZDB-GENE-030909-12
Name
GTP binding protein 1
Symbol
gtpbp1 Nomenclature History
Previous Names
  • cb858 (1)
  • wu:fb36e06
  • wu:fi39g05
  • zgc:66228
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Is expressed in intermediate cell mass of mesoderm; intermediate mesoderm; lens; solid lens vesicle; and ventral mesoderm. Orthologous to human GTPBP1 (GTP binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa10030Allele with one point mutationUnknownPremature StopENU
sa33222Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With gtpbp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with characteristic facial and ectodermal features and tetraparesis 1 620888
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Associated With gtpbp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR035531 GTP binding protein 1-like, GTP-binding domain
Family IPR050055 Elongation factor Tu GTPase
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
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Domain Details Per Protein
Protein Length Elongation factor Tu GTPase GTP binding protein 1-like, GTP-binding domain P-loop containing nucleoside triphosphate hydrolase Translational (tr)-type GTP-binding domain Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily
UniProtKB:A0A8M2BB58 652
UniProtKB:A0A8M9PEZ2 639
UniProtKB:Q6PFN0 642
UniProtKB:A0A8M2BBB3 670
UniProtKB:A0A8N1TRQ8 657
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gtpbp1-201 (1) Ensembl 3,219 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-283B1ZFIN Curated Data
EncodesESTcb858Thisse et al., 2001
EncodesESTfb36e06ZFIN Curated Data
EncodesESTfi39g05ZFIN Curated Data
EncodescDNAMGC:66228ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanGTPBP122
Conserved genome location (synteny) (2)
Amino acid sequence comparison (2)
MouseGtpbp115
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 10
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