Gene

gtpbp1

ID
ZDB-GENE-030909-12
Name
GTP binding protein 1
Symbol
gtpbp1 Nomenclature History
Previous Names
  • cb858 (1)
  • wu:fb36e06
  • wu:fi39g05
  • zgc:66228
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have translation elongation factor activity. Predicted to be involved in translational elongation. Is expressed in intermediate cell mass of mesoderm; intermediate mesoderm; lens; solid lens vesicle; and ventral mesoderm. Orthologous to human GTPBP1 (GTP binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gtpbp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with characteristic facial and ectodermal features and tetraparesis 1 620888
Associated With gtpbp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR035531 GTP binding protein 1-like, GTP-binding domain
Family IPR050055 Elongation factor Tu GTPase
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Elongation factor Tu GTPase GTP binding protein 1-like, GTP-binding domain P-loop containing nucleoside triphosphate hydrolase Translational (tr)-type GTP-binding domain Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily
UniProtKB:A0A8M2BB58 652
UniProtKB:A0A8M9PEZ2 639
UniProtKB:Q6PFN0 642
UniProtKB:A0A8M2BBB3 670
UniProtKB:A0A8N1TRQ8 657
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA gtpbp1-201 (1) Havana 3219 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations