Gene
pde6gb
- ID
- ZDB-GENE-030904-1
- Name
- phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b
- Symbol
- pde6gb Nomenclature History
- Previous Names
-
- pde6g (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Is expressed in epidermis; epiphysis; retina; and retinal rod cell. Orthologous to human PDE6G (phosphodiesterase 6G).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55991 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 57 | Alliance | Retinitis pigmentosa 57 | 613582 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Retinal cGMP phosphodiesterase, gamma subunit | Retinal cGMP phosphodiesterase, gamma subunit superfamily |
|---|---|---|---|
|
UniProtKB:Q7ZVI5
|
87 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pde6gb-201
(1)
|
Ensembl | 1,711 nt |
Interactions and Pathways
No data available
Plasmids
No data available